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Anti-KCNQ2 (Polyclonal), ALEXA Fluor 594

Anti-KCNQ2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKCNQ2
SpecificityThis antibody reacts specifically with KCNQ2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human KCNQ2
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Benign familial neonatal convulsions (BFNC), Both proteins display a broad distribution within the brain, Epilepsy results from an electrical hyperexcitability in the central nervous system, KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains, Potassium channels are important regulators of electrical signaling, an autosomal dominant epilepsy of infancy, determining the firing properties and responsiveness of a variety of neurons, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes, with expression patterns that largely overlap, &euro, &trade, 5% of the worldâ, Epilepsy affects about 0, s population and has a large genetic component
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Kv7, 2 ENB1 BFNC KCNA11 HNSPC
Also known asKCNQ2 Polyclonal Antibody
Other nameAnti-KCNQ2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKCNQ2
Short nameAnti-KCNQ2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-KCNQ2 (polyclonal)
Alternative techniquepolyclonals
Identity 6296
Gene KCNQ2
Long gene name potassium voltage-gated channel subfamily Q member 2
Synonyms gene EBN EBN1
Synonyms gene name KQT-like subfamily, member 2 , member 2 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q
Locus 20q13, 33
Discovery year 1998-01-12
GenBank acession AF033348
Entrez gene record 3785
Pubmed identfication 9425895 16382104
RefSeq identity NM_172109
Classification Potassium voltage-gated channels
Havana BLAST/BLAT OTTHUMG00000033049

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