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Anti-KCNT2 (Polyclonal), ALEXA Fluor 594

Anti-KCNT2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKCNT2
SpecificityThis antibody reacts specifically with KCNT2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human KCNT2
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Its channel activity is inhibited by ATP, KCNT2 is a 1, KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels, There are four isoforms of KCNT2 that are produced as a result of alternative splicing events, and upon stimulation of G-protein coupled receptors, controlling the repolarization and the frequency of action potentials in neurons, inhalation anesthetics, muscles and other excitable cells, such as isoflourane, such as mAChR M1 and GluR-1, 135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins, Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KCa4, 1 , 2 SLICK SLO2
Also known asKCNT2 Polyclonal Antibody
Other nameAnti-KCNT2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKCNT2
Short nameAnti-KCNT2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-KCNT2 (polyclonal)
Alternative techniquepolyclonals
Identity 18866
Gene KCNT2
Long gene name potassium sodium-activated channel subfamily T member 2
Synonyms gene name member 2 , member 2 potassium channel, potassium channel, sodium activated subfamily T, subfamily T
Synonyms name sodium and chloride activated ATP sensitive potassium channel
Locus 1q31, 3
Discovery year 2002-07-10
GenBank acession BX647852 AY359444 AK127807
Entrez gene record 343450
Pubmed identfication 16382103
RefSeq identity NM_198503
Classification Potassium sodium-activated channel subfamily T
Havana BLAST/BLAT OTTHUMG00000035611

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