Name : Anti-KCNT2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8675907276
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | KCNT2 |
| Specificity | This antibody reacts specifically with KCNT2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human KCNT2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Its channel activity is inhibited by ATP, KCNT2 is a 1, KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels, There are four isoforms of KCNT2 that are produced as a result of alternative splicing events, and upon stimulation of G-protein coupled receptors, controlling the repolarization and the frequency of action potentials in neurons, inhalation anesthetics, muscles and other excitable cells, such as isoflourane, such as mAChR M1 and GluR-1, 135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins, Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KCa4, 1 , 2 SLICK SLO2 |
| Also known as | KCNT2 Polyclonal Antibody |
| Other name | Anti-KCNT2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | KCNT2 |
| Short name | Anti-KCNT2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-KCNT2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 18866 |
| Gene | KCNT2 |
| Long gene name | potassium sodium-activated channel subfamily T member 2 |
| Synonyms gene name | member 2 , member 2 potassium channel, potassium channel, sodium activated subfamily T, subfamily T |
| Synonyms name | sodium and chloride activated ATP sensitive potassium channel |
| Locus | 1q31, 3 |
| Discovery year | 2002-07-10 |
| GenBank acession | BX647852 AY359444 AK127807 |
| Entrez gene record | 343450 |
| Pubmed identfication | 16382103 |
| RefSeq identity | NM_198503 |
| Classification | Potassium sodium-activated channel subfamily T |
| Havana BLAST/BLAT | OTTHUMG00000035611 |