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Anti-KDM5A (Polyclonal) , ALEXA Fluor 594

Anti-KDM5A (Polyclonal) , ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKDM5A
SpecificityThis antibody reacts specifically with KDM5A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human KDM5A
Gene ID5927
Swiss ProtP29375
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', In a histone demethylase-independent manner, May be involved in transcriptional regulation of Hox proteins during cell differentiation, May participate in transcriptional repression of cytokines such as CXCL12, May stimulate transcription mediated by nuclear receptors, Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity), thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asKDM5A Polyclonal Antibody
Other nameAnti-KDM5A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKDM5A
Short nameAnti-KDM5A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-KDM5A (polyclonal)
Alternative techniquepolyclonals
Identity 9886
Gene KDM5A
Long gene name lysine demethylase 5A
Synonyms gene RBBP2 JARID1A
Synonyms gene name AT rich interactive domain 1A (RBBP2-like) jumonji, AT rich interactive domain 1A lysine (K)-specific demethylase 5A , retinoblastoma-binding protein 2 Jumonji
Locus 12p13, 33
Discovery year 1992-09-17
Entrez gene record 5927
Pubmed identfication 1857421
RefSeq identity NM_005056
Classification PHD finger proteins Lysine demethylases AT-rich interaction domain containing EMSY complex
Havana BLAST/BLAT OTTHUMG00000168055

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