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Anti-KDM5B (Polyclonal), ALEXA Fluor 594

Anti-KDM5B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKDM5B
SpecificityThis antibody reacts specifically with KDM5B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
Gene ID10765
Swiss ProtQ9UGL1
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a transcriptional corepressor for FOXG1B and PAX9, Demethylates trimethylated, Does not demethylate histone H3 'Lys-9' or H3 'Lys-27', Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5, In contrast, Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity), dimethylated and monomethylated H3 'Lys-4', may act as a tumor suppressor for melanoma, thereby playing a central role in histone code, Histone demethylase that demethylates 'Lys-4' of histone H3
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RBBP2H1A PLU-1 CT31 PPP1R98
Also known asKDM5B Polyclonal Antibody
Other nameAnti-KDM5B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKDM5B
Short nameAnti-KDM5B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-KDM5B (polyclonal)
Alternative techniquepolyclonals
Identity 18039
Gene KDM5B
Long gene name lysine demethylase 5B
Synonyms gene JARID1B
Synonyms gene name AT rich interactive domain 1B (RBP2-like) jumonji, AT rich interactive domain 1B lysine (K)-specific demethylase 5B , Jumonji
Synonyms name cancer/testis antigen 31 protein phosphatase 1, regulatory subunit 98
Locus 1q32, 1
Discovery year 2004-01-28
GenBank acession AJ243706
Entrez gene record 10765
Pubmed identfication 11483573 11478881
RefSeq identity NM_006618
Classification PHD finger proteins Lysine demethylases AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000041401

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