Filters

Anti-Kir6.2(Thr224) (Polyclonal), ALEXA Fluor 594

Anti-Kir6.2(Thr224) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/Peptide2 Thr224, Kir6
Specificity2(Thr224), This antibody reacts specifically with Kir6
ModificationPhosphorylation
Modification siteThr224
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen Source2 around the phosphorylation site of Thr224, KLH conjugated synthetic phosphopeptide derived from human Kir6
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene, Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), The encoded protein, The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, [provided by RefSeq], an autosomal recessive disorder characterized by unregulated insulin secretion, and permanent neonatal diabetes mellitus (PNDM), is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR, transient neonatal diabetes mellitus type 3 (TNDM3), where they participate in a wide range of physiologic responses, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, Potassium channels are present in most mammalian cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ATP sensitive inward rectier potassium channel 11, BIR, Beta cell inward rectier subunit, HHF 2, HHF2, IKATP, IRK 11, IRK11, Inward rectier K+ channel Kir6, Inwardly rectying potassium channel KIR6, KCNJ11, Kir 6, Kir6, MGC133230, PHHI, Potassium channel, Potassium inwardly rectying channel J11, TNDM 3, TNDM3, inwardly rectying subfamily J member 11, mBIR, 2, 2, 2, 2, 2 phospho T224, p-Kir6
Also known as2(Thr224) Polyclonal Antibody, Kir6
Other name2(Thr224) Polyclonal, Anti-Kir6
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target2(Thr224), Kir6
Short name2(Thr224) (Polyclonal) Fluor 594, Anti-Kir6
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, 2(Thr224) (polyclonal), antibody to-Kir6
Alternative techniquepolyclonals

Subscribe to our Newsletter