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Anti-Kisspeptin (Polyclonal), ALEXA Fluor 594

Anti-Kisspeptin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideKisspeptin
SpecificityKisspeptin, This antibody detects Kisspeptin-10 region of Kisspeptin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Kiss-1
Gene ID3814
Swiss ProtQ15726
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation of the receptor inhibits cell proliferation and cell migration, Generates a C-terminally amidated peptide, Kp-1, Kp-1 is a decapeptide derived from the primary translation product, Kp-1 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself, May regulate events downstream of cell-matrix adhesion, The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood, The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts, isolated in conditioned medium of first trimester trophoblast, key characteristics of tumor metastasis, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54, perhaps involving cytoskeletal reorganization, Metastasis suppressor protein in malignant melanomas and in some breast cancers
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asKisspeptin Polyclonal Antibody
Other nameAnti-Kisspeptin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetKisspeptin
Short nameAnti-Kisspeptin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Kisspeptin (polyclonal)
Alternative techniquepolyclonals
Identity 6341
Gene KISS1
Long gene name KiSS-1 metastasis-suppressor
Synonyms name prepro-kisspeptin kisspeptin
Locus 1q32, 1
Discovery year 1998-05-18
GenBank acession U43527
Entrez gene record 3814
Pubmed identfication 9192814 9806840
RefSeq identity NM_002256
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000036060

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