Name : Anti-LCA5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1424723410
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | LCA5 |
| Specificity | This antibody reacts specifically with LCA5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human LCA5 |
| Gene ID | 167691 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | LCA5, Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation, The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family, These proteins are involved in processes such as photoreceptor development and maintenance, also known as Lebercilin, centrioles and primary cilia of cultured mammalian cells, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, phototransduction, vitamin A metabolism and protein trafficking, Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | LCA5 Polyclonal Antibody |
| Other name | Anti-LCA5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | LCA5 |
| Short name | Anti-LCA5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-LCA5 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 31923 |
| Gene | LCA5 |
| Long gene name | LCA5, lebercilin |
| Synonyms gene | C6orf152 |
| Synonyms gene name | chromosome 6 open reading frame 152 Leber congenital amaurosis 5 |
| Locus | 6q14, 1 |
| Discovery year | 2005-02-23 |
| Entrez gene record | 167691 |
| Pubmed identfication | 10631161 17546029 |
| RefSeq identity | NM_181714 |
| Havana BLAST/BLAT | OTTHUMG00000015080 |