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Anti-LCA5 (Polyclonal), ALEXA Fluor 594

Anti-LCA5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLCA5
SpecificityThis antibody reacts specifically with LCA5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human LCA5
Gene ID167691
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information LCA5, Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation, The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family, These proteins are involved in processes such as photoreceptor development and maintenance, also known as Lebercilin, centrioles and primary cilia of cultured mammalian cells, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, phototransduction, vitamin A metabolism and protein trafficking, Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asLCA5 Polyclonal Antibody
Other nameAnti-LCA5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLCA5
Short nameAnti-LCA5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-LCA5 (polyclonal)
Alternative techniquepolyclonals
Identity 31923
Gene LCA5
Long gene name LCA5, lebercilin
Synonyms gene C6orf152
Synonyms gene name chromosome 6 open reading frame 152 Leber congenital amaurosis 5
Locus 6q14, 1
Discovery year 2005-02-23
Entrez gene record 167691
Pubmed identfication 10631161 17546029
RefSeq identity NM_181714
Havana BLAST/BLAT OTTHUMG00000015080

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