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Anti-Legumain (Polyclonal), ALEXA Fluor 594

Anti-Legumain (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLegumain
SpecificityThis antibody reacts specifically with Legumain
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsLysosome
Antigen SourceKLH conjugated synthetic peptide derived from human Legumain
Gene ID5641
Swiss ProtQ99538
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Can also cleave aspartyl bonds slowly, May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system, Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity), Required for normal degradation of internalized EGFR, Required for normal lysosomal protein degradation in renal proximal tubules, especially under acidic conditions, Has a strict specificity for hydrolysis of asparaginyl bonds
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asLegumain Polyclonal Antibody
Other nameAnti-Legumain Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLegumain
Short nameAnti-Legumain (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Legumain (polyclonal)
Alternative techniquepolyclonals
Identity 23079
Gene LGMNP1
Long gene name legumain pseudogene 1
Synonyms gene LGMN2P
Synonyms gene name legumain 2 pseudogene
Locus 13q21, 31
Discovery year 2003-09-03
Entrez gene record 122199
RefSeq identity NG_001534
Havana BLAST/BLAT OTTHUMG00000017029

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