Name : Anti-Leupaxin (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1505189358
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Leupaxin |
| Specificity | This antibody reacts specifically with Leupaxin |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Leupaxin |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Consisting of four leucine-rich LD-motifs at the N-terminus and four LIM domains at the C-terminus, Leupaxin is a substrate for tyrosine kinase in lymphoid cells and is suggested to participate in and be regulated by tyrosine kinase activity, Leupaxin is highly expressed in lymphoid tissues such as spleen, Leupaxin may be a potential progression marker for a subset of prostate cancer and may act as a novel coactivator of the androgen receptor, PYK2, The leupaxin and PYK2 complex is involved in cell type-specific signaling in which it regulates signaling at sites of adhesion, in lymphoid cells, leupaxin associates with a member of the focal adhesion kinase family, lymph node, thymus and appendix, with low expression in bone marrow and fetal liver, Leupaxin is a 386 amino acid cytoplasmic protein and member of the paxillin family |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | LDPL |
| Also known as | Leupaxin Polyclonal Antibody |
| Other name | Anti-Leupaxin Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Leupaxin |
| Short name | Anti-Leupaxin (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Leupaxin (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 14061 |
| Gene | LPXN |
| Long gene name | leupaxin |
| Locus | 11q12, 1 |
| Discovery year | 2000-11-28 |
| GenBank acession | AF062075 |
| Entrez gene record | 9404 |
| Pubmed identfication | 9565592 |
| RefSeq identity | NM_004811 |
| Classification | LIM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167466 |