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Anti-Leupaxin (Polyclonal), ALEXA Fluor 594

Anti-Leupaxin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLeupaxin
SpecificityThis antibody reacts specifically with Leupaxin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Leupaxin
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Consisting of four leucine-rich LD-motifs at the N-terminus and four LIM domains at the C-terminus, Leupaxin is a substrate for tyrosine kinase in lymphoid cells and is suggested to participate in and be regulated by tyrosine kinase activity, Leupaxin is highly expressed in lymphoid tissues such as spleen, Leupaxin may be a potential progression marker for a subset of prostate cancer and may act as a novel coactivator of the androgen receptor, PYK2, The leupaxin and PYK2 complex is involved in cell type-specific signaling in which it regulates signaling at sites of adhesion, in lymphoid cells, leupaxin associates with a member of the focal adhesion kinase family, lymph node, thymus and appendix, with low expression in bone marrow and fetal liver, Leupaxin is a 386 amino acid cytoplasmic protein and member of the paxillin family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LDPL
Also known asLeupaxin Polyclonal Antibody
Other nameAnti-Leupaxin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLeupaxin
Short nameAnti-Leupaxin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Leupaxin (polyclonal)
Alternative techniquepolyclonals
Identity 14061
Gene LPXN
Long gene name leupaxin
Locus 11q12, 1
Discovery year 2000-11-28
GenBank acession AF062075
Entrez gene record 9404
Pubmed identfication 9565592
RefSeq identity NM_004811
Classification LIM domain containing
Havana BLAST/BLAT OTTHUMG00000167466

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