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Anti-LGI4 (Polyclonal), ALEXA Fluor 594

Anti-LGI4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLGI4
SpecificityThis antibody reacts specifically with LGI4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human LGI4
Gene ID163175
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ER and vesicles, Interestingly, LGI1, LGI2 and LGI3, LGI4 is localized subcellularly to the Golgi, LGI4 shares significant homology with its other family members, Significantly, There are two isoforms of LGI4 that are produced as a result of alternative splicing events, also known as leucine-rich glioma-inactivated protein 4, given the sequence similarity of LGI4, is a 537 amino acid secreted glycosylated protein that is widely expressed, it is likely that it also may be implicated in the pathology of seizures, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation, with highest levels found within the nervous system, LGI4
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asLGI4 Polyclonal Antibody
Other nameAnti-LGI4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLGI4
Short nameAnti-LGI4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-LGI4 (polyclonal)
Alternative techniquepolyclonals
Identity 18712
Gene LGI4
Long gene name leucine rich repeat LGI family member 4
Synonyms gene name leucine-rich repeat LGI family, member 4
Locus 19q13, 12
Discovery year 2002-05-30
GenBank acession AJ487519
Entrez gene record 163175
Pubmed identfication 12023020
Havana BLAST/BLAT OTTHUMG00000044558

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