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Anti-LIMK1(Thr508)/LIMK2(Thr505), ALEXA Fluor 594

Anti-LIMK1(Thr508)/LIMK2(Thr505), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLIMK1 Thr508/LIMK2 Thr505
SpecificityThis antibody reacts specifically with LIMK1(Thr508)/LIMK2(Thr505)
ModificationPhosphorylation
Modification siteThr505
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
Gene ID3984
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Detected ubiquitously throughout the different regions of adult brain, Expressed to a lesser extent in heart and skeletal muscle, LIMK1 may be involved in brain development, Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, it is highly expressed in both adult and fetal nervous system, thereby stabilizing the actin cytoskeleton, with highest levels in the cerebral cortex, LIMK1 is a protein kinase which regulates actin filament dynamics
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asLIMK1(Thr508)/LIMK2(Thr505) Antibody
Other nameAnti-LIMK1(Thr508)/LIMK2(Thr505)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetLIMK1(Thr508)/LIMK2(Thr505)
Short nameAnti-LIMK1(Thr508)/LIMK2(Thr505) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-LIMK1(Thr508)/LIMK2(Thr505)
Identity 6614
Gene LIMK2
Long gene name LIM domain kinase 2
Locus 22q12, 2
Discovery year 1997-08-28
GenBank acession D45906
Entrez gene record 3985
Pubmed identfication 8537403 10591208
RefSeq identity NM_016733
Classification LIM domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000151251

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