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Anti-LLGL1 + LLGL2(Ser650+Ser654), ALEXA Fluor 594

Anti-LLGL1 + LLGL2(Ser650+Ser654), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLLGL1 + LLGL2 Ser650+Ser654
SpecificityThis antibody reacts specifically with LLGL1 + LLGL2(Ser650+Ser654)
ModificationPhosphorylation
Modification siteSer650+Ser654
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
Gene ID3996
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In fly, In human, LLGL2 is a protein similar to lethal giant larvae of Drosophila, The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17, The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC), this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells, LLGL1 is a protein that is similar to a tumor suppressor in Drosophila
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HGL Hugl-2
Also known asLLGL1 + LLGL2(Ser650+Ser654) Antibody
Other nameAnti-LLGL1 + LLGL2(Ser650+Ser654)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetLLGL1 + LLGL2(Ser650+Ser654)
Short nameAnti-LLGL1 + LLGL2(Ser650+Ser654) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-lethal giant larvae homolog 1 (Drosophila) and lethal giant larvae homolog 2 (Drosophila)(Ser650+Ser654)
Alternative to gene target BT, Cytoplasm, Cytoplasm, DLG4 and HUGL and HUGL-1 and HUGL1 and LLGL, HGL and LGL2, LLGL1 and IDBG-33645 and ENSG00000131899 and 3996, LLGL1 and IDBG-638036 and ENSBTAG00000004635 and 781865, LLGL2 and IDBG-68503 and ENSG00000073350 and 3993, Llgl1 and IDBG-181336 and ENSMUSG00000020536 and 16897, Llgl2 and IDBG-214360 and ENSMUSG00000020782 and 217325, PDZ domain binding, lethal giant larvae homolog 2 (Drosophila), protein kinase binding, this GO :0000137 and this GO lgi cis cisterna and cellular component this GO :0000139 and this GO lgi membrane and cellular component this GO :0005097 and Rab GTPase activator activity and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006887 and exocytosis and biological process this GO :0006893 and this GO lgi to plasma membrane transport and biological process this GO :0007409 and axonogenesis and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030424 and axon and cellular component this GO :0030864 and cortical actin cytoskeleton and cellular component this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031901 and early endosome membrane and cellular component this GO :0032588 and trans- this GO lgi network membrane and cellular component this GO :0032851 and positive regulation of Rab GTPase activity and biological process this GO :0035090 and maintenance of apical/basal cell polarity and biological process this GO :0035748 and myelin sheath abaxonal region and cellular component, this GO :0005097: Rab GTPase activator activity, this GO :0005097: Rab GTPase activator activity and also this GO :0005198: structural molecule activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005198: structural molecule activity, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006887 and exocytosis and biological process this GO :0007049 and cell cycle and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0032878 and regulation of establishment or maintenance of cell polarity and biological process this GO :0051301 and cell division and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0030165: PDZ domain binding, this GO :0019901: protein kinase binding, this GO :0030165: PDZ domain binding, 52154 and IDBG-643198 and ENSBTAG00000020067 and 539545, lethal giant larvae homolog 1 (Drosophila)
Identity 6629
Gene LLGL2
Long gene name LLGL2, scribble cell polarity complex component
Synonyms gene name lethal giant larvae homolog 2 (Drosophila) lethal giant larvae homolog 2, scribble cell polarity complex component
Locus 17q25, 1
Discovery year 1997-01-28
GenBank acession X87342
Entrez gene record 3993
Pubmed identfication 22580609
RefSeq identity NM_004524
Classification Scribble complex WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000179685

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