Anti-LMX1b/NPS1 (Polyclonal), ALEXA Fluor 594

Anti-LMX1b/NPS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	LMX1b/NPS1
Specificity	This antibody reacts specifically with LMX1b/NPS1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human LMX1b/NPS1
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	In addition, LMX1B along with LIM1 control the initial trajectory of motor axons in the developing mammalian limb, LMX1B belongs to the LIM-homeodomain family, LMX1B directly regulates the coordinated expression of alpha 3(IV) and alpha 4(IV) collagen required for normal glomerular basement membrane (GBM) morphogenesis, LMX1B is also necessary for normal development of the eye and in regulating dopaminergic neurogenesis and may be involved in developmental glaucoma and the aetiology of idiopathic Parkinsonâ, NPS is caused by putative loss-of-function mutations in the transcription factor LMX1B, Specifically, Twenty-two novel mutations may occur in the gene encoding LMX1B and the type and distribution of the mutations support the hypothesis that NPS is the result of haploinsufficiency for LMX1B, and the dysregulation of LMX1B in GBM contributes to the renal pathology and nephrosis in NPS, frequently, members of which are known to be important for pattern formation during development, renal disease, skeletal anomalies and, &euro, &trade, Nail-patella syndrome (NPS) is an autosomal dominant disorder characterized by dyplasia of finger nails, s disease
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	LMX1b/NPS1 Polyclonal Antibody
Other name	Anti-LMX1b/NPS1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	LMX1b/NPS1
Short name	Anti-LMX1b/NPS1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-LMX1b/NPS1 (polyclonal)
Alternative technique	polyclonals
Identity	6654
Gene	LMX1B
Long gene name	LIM homeobox transcription factor 1 beta
Synonyms gene	NPS1
Synonyms gene name	LIM homeobox transcription factor 1, beta
Locus	9q33, 3
Discovery year	1998-02-11
GenBank acession	U77457
Entrez gene record	4010
Pubmed identfication	9441763 9590287
Classification	LIM class homeoboxes
Havana BLAST/BLAT	OTTHUMG00000020692
Locus Specific Databases	LRG_1014

Anti-LMX1b/NPS1 (Polyclonal), ALEXA Fluor 594

Anti-LMX1b/NPS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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