Anti-LOX 1 (Polyclonal), ALEXA Fluor 594

Anti-LOX 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	LOX 1
Specificity	This antibody reacts specifically with LOX 1
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from Rabbit LOX-1
Gene ID	100009322
Swiss Prot	Q9XTA8
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Also acts as a receptor for advanced glycation end (AGE) products, Also involved in inflammatory process, In addition to binding oxLDL, Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, activated platelets, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity), by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, monocyte adhesion and apoptosis, monocytes, pro-oxidative conditions and apoptosis, resulting in pro-inflammatory responses, thereby participating in cell-mediated antigen cross-presentation, Receptor that mediates the recognition
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	LOX 1 Polyclonal Antibody
Other name	Anti-LOX 1 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	LOX 1
Short name	Anti-LOX 1 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-LOX 1 (polyclonal)
Alternative technique	polyclonals
Identity	6664
Gene	LOX
Long gene name	lysyl oxidase
Locus	5q23, 1
Discovery year	1986-01-01
Entrez gene record	4015
Pubmed identfication	1685472
Havana BLAST/BLAT	OTTHUMG00000128914
Locus Specific Databases	ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Anti-LOX 1 (Polyclonal), ALEXA Fluor 594

Anti-LOX 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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