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Anti-LRP1(Ser4523) (Polyclonal), ALEXA Fluor 594
Anti-LRP1(Ser4523) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516
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BIOSS POLYCLONAL ANTIBODIES
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516
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100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | LRP1 Ser4523 |
| Specificity | This is the corresponding phosphorylation site in the following species: mouse ser(4524) rat ser(4524)LRP1(Ser4523) |
| Modification | Phosphorylation |
| Modification site | Ser4523 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523 |
| Gene ID | 4035 |
| Swiss Prot | Q07954 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Functions as a receptor for Pseudomonas aeruginosa exotoxin A, Involved in cellular lipid homeostasis, Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), May modulate cellular events, Required for early embryonic development, as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission, such as APP metabolism, Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | SUNCOR SUN-CoR LRP1 Rrp47 |
| Also known as | LRP1(Ser4523) Polyclonal Antibody |
| Other name | Anti-LRP1(Ser4523) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | LRP1(Ser4523) |
| Short name | Anti-LRP1(Ser4523) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-low density lipoprotein receptor-related protein 1(Ser4523) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | A2MR and APOER and APR and CD91 and IGFBP3R and LRP and LRP1A and TGFBR5, LRP1 and IDBG-42176 and ENSG00000123384 and 4035, LRP1 and IDBG-635332 and ENSBTAG00000010830 and 533894, Lrp1 and IDBG-195360 and ENSMUSG00000040249 and 16971, lipoprotein particle receptor binding, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0002020 and protease binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0007603 and phototransduction, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0004872: receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0032403: protein complex binding and also this GO :0034185: apolipoprotein binding and also this GO :0042954: lipoprotein transporter activity and also this GO :0044822: poly(A) RNA binding and also this GO :0070325: lipoprotein particle receptor binding, this GO :0004872: receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0032403: protein complex binding, this GO :0034185: apolipoprotein binding, this GO :0042954: lipoprotein transporter activity, this GO :0044822: poly(A) RNA binding, this GO :0070325: lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030136 and clathrin-coated vesicle and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030425 and dendrite and cellular component this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0032370 and positive regulation of lipid transport and biological process this GO :0032374 and regulation of cholesterol transport and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032429 and regulation of phospholipase A2 activity and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0035909 and aorta morphogenesis and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0042954 and lipoprotein transporter activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043277 and apoptotic cell clearance and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0051222 and positive regulation of protein transport and biological process this GO :0070325 and lipoprotein particle receptor binding and molecular function this GO :0097242 and beta-amyloid clearance and biological process this GO :2000587 and negative regulation of platelet-derived growth factor receptor-beta signaling pathway and biological process, low density lipoprotein receptor-related protein 1 |
| Identity | 29911 |
| Gene | C1D |
| Long gene name | C1D nuclear receptor corepressor |
| Synonyms gene name | C1D nuclear receptor co-repressor |
| Synonyms name | small unique nuclear receptor co-repressor |
| Locus | 2p14 |
| Discovery year | 2009-02-06 |
| Entrez gene record | 10438 |
| Pubmed identfication | 9469821 17599775 17412707 11801738 9405624 |
| RefSeq identity | NM_006333 |
| Havana BLAST/BLAT | OTTHUMG00000129564 |