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Anti-LRP5L (Polyclonal), ALEXA Fluor 594

Anti-LRP5L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLRP5L
SpecificityThis antibody reacts specifically with LRP5L
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human LRP5L
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information However, LRP is expressed in rat tibia, LRP5 affects bone mass accrual during growth, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family, LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway, LRP5 is most closely related to LRP1, LRP5L is a related protein that exists as two isoforms produced by alternative splicing, LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG), Of the known family members, VLDLR (very low density lipoprotein receptor) and ApoER2, YWTD repeats and an O-linked sugar domain, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, including LDLR (low density lipo-protein receptor), specifically in areas of the bone that are involved in remodeling, Members of the LDL receptor gene family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DKFZp434O0213
Also known asLRP5L Polyclonal Antibody
Other nameAnti-LRP5L Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLRP5L
Short nameAnti-LRP5L (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-low density lipoprotein receptor-related protein 5-like (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target LRP5L and IDBG-3018 and ENSG00000100068 and 91355, Wnt-activated receptor activity, multiple, this GO :0017147 and Wnt-protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process, this GO :0017147: Wnt-protein binding, this GO :0017147: Wnt-protein binding and also this GO :0042813: Wnt-activated receptor activity, this GO :0042813: Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5-like
Identity 25323
Gene LRP5L
Long gene name LDL receptor related protein 5 like
Synonyms gene name low density lipoprotein receptor-related protein 5-like
Locus 22q11, 23
Discovery year 2005-10-09
GenBank acession AL137651
Entrez gene record 91355
RefSeq identity NM_182492
Havana BLAST/BLAT OTTHUMG00000150900

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