Filters

Anti-LRRFIP1 (Polyclonal), ALEXA Fluor 594

Anti-LRRFIP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLRRFIP1
SpecificityThis antibody reacts specifically with LRRFIP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human LRRFIP1
Gene ID9208
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Flightless I has a C-terminal TaR-like domain which binds Actin and therefore the association of LRRFIP1 with the LRR of Flightless I may provide a link between the Actin cytoskeleton and RNA in mammalian cells, In contrast, LRRFIP1 binds double-stranded RNA with high affinity, LRRFIP1 does not bind single-stranded DNA or RNA significantly and binds double-stranded DNA weakly, LRRFIP1 is also believed to control smooth muscle cell proliferation following arterial injury through PDGF-A repression, The N-terminus of LRRFIP1 shows high homology to the coiled-coil domain of FLAP, The RNA binding domain has been identified and encompasses a lysine-rich motif, a protein which binds the leucine-rich repeat (LRR) of Flightless I, and the interaction of LRRFIP1 with the LRR of Flightless I has been confirmed, and two molecules of LRRFIP1 bind the TaR stem, LRRFIP1 is an 738 amino acid human protein whose rodent counterpart is known as Lrrfip1 (also designated FLAP in mouse)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLAP-1 FLIIAP1 TRIP GCF-2 HUFI-1
Also known asLRRFIP1 Polyclonal Antibody
Other nameAnti-LRRFIP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLRRFIP1
Short nameAnti-LRRFIP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-LRRFIP1 (polyclonal)
Alternative techniquepolyclonals
Identity 6702
Gene LRRFIP1
Long gene name LRR binding FLII interacting protein 1
Synonyms gene name leucine rich repeat (in FLII) interacting protein 1
Synonyms name GC-binding factor 2
Locus 2q37, 3
Discovery year 1999-02-15
GenBank acession AJ223075
Entrez gene record 9208
Pubmed identfication 9705290 9525888 16199883
RefSeq identity NM_004735
Havana BLAST/BLAT OTTHUMG00000133339

Subscribe to our Newsletter