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Anti-Lubricin/SZP (Polyclonal), ALEXA Fluor 594

Anti-Lubricin/SZP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideLubricin/SZP
SpecificityThis antibody reacts specifically with Lubricin/SZP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Lubricin/SZP
Gene ID6401
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule, Defects in the gene encoding for lubricin can cause Jakobs syndrome, It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage, Lubricin inhibits synovial cell adhesion to the cartilage surface, Lubricin is highly expressed in cartilage, Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), also designated proteoglycan-4 or megakaryocyte stimulating factor, but also prevents the deposition of proteins from synovial fluid onto cartilage, is important for boundary lubrication within articulating joints, liver and synovial tissue, Lubricin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms JCAP SZP MSF HAPO bG174L6, 2 FLJ32635
Also known asLubricin/SZP Polyclonal Antibody
Other nameAnti-Lubricin/SZP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetLubricin/SZP
Short nameAnti-Lubricin/SZP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Lubricin/SZP (polyclonal)
Alternative techniquepolyclonals
Identity 9364
Gene PRG4
Long gene name proteoglycan 4
Synonyms gene CACP
Synonyms gene name (megakaryocyte stimulating factor, arthropathy, articular superficial zone protein, camptodactyly, coxa vara, pericarditis syndrome) , proteoglycan 4
Synonyms name arthropathy, coxa vara, lubricin megakaryocyte stimulating factor articular superficial zone protein Jacobs camptodactyly-arthropathy-pericarditis syndrome camptodactyly, pericarditis syndrome bG174L6, 2 (MSF: megakaryocyte stimulating factor )
Locus 1q31, 1
Discovery year 2000-07-31
GenBank acession U70136
Entrez gene record 10216
Pubmed identfication 10545950 9920774
RefSeq identity NM_005807
Havana BLAST/BLAT OTTHUMG00000035574

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