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Anti-M-CSF Receptor(Tyr708), ALEXA Fluor 594

Anti-M-CSF Receptor(Tyr708), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideM-CSF Receptor Tyr708
SpecificityThis antibody reacts specifically with M-CSF Receptor(Tyr708)
ModificationPhosphorylation
Modification siteTyr708
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 708
Gene ID1436
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CD115 is expressed by cells of the monocytic lineage and by progenitor cells, Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation, Mutations in this gene have been associated with a predisposition to myeloid malignancy, The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains, This receptor mediates most if not all of the biological effects of this cytokine, a cytokine which controls the production, and function of macrophages, differentiation, This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms M-CSF MCSF MGC31930
Also known asM-CSF Receptor(Tyr708) Antibody
Other nameAnti-M-CSF Receptor(Tyr708)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetM-CSF Receptor(Tyr708)
Short nameAnti-M-CSF Receptor(Tyr708) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-M-CSF Receptor(Tyr708)
Identity 2432
Gene CSF1
Long gene name colony stimulating factor 1
Synonyms gene name colony stimulating factor 1 (macrophage)
Synonyms name macrophage colony stimulating factor 1
Locus 1p13, 3
Discovery year 1986-01-01
GenBank acession BC021117
Entrez gene record 1435
Pubmed identfication 1540160
RefSeq identity NM_000757
Havana BLAST/BLAT OTTHUMG00000011646

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