Name : Anti-M-CSF Receptor(Tyr708), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN3228604552
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | M-CSF Receptor Tyr708 |
| Specificity | This antibody reacts specifically with M-CSF Receptor(Tyr708) |
| Modification | Phosphorylation |
| Modification site | Tyr708 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 708 |
| Gene ID | 1436 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CD115 is expressed by cells of the monocytic lineage and by progenitor cells, Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation, Mutations in this gene have been associated with a predisposition to myeloid malignancy, The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains, This receptor mediates most if not all of the biological effects of this cytokine, a cytokine which controls the production, and function of macrophages, differentiation, This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | M-CSF MCSF MGC31930 |
| Also known as | M-CSF Receptor(Tyr708) Antibody |
| Other name | Anti-M-CSF Receptor(Tyr708) |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | M-CSF Receptor(Tyr708) |
| Short name | Anti-M-CSF Receptor(Tyr708) Fluor 594 |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-M-CSF Receptor(Tyr708) |
| Identity | 2432 |
| Gene | CSF1 |
| Long gene name | colony stimulating factor 1 |
| Synonyms gene name | colony stimulating factor 1 (macrophage) |
| Synonyms name | macrophage colony stimulating factor 1 |
| Locus | 1p13, 3 |
| Discovery year | 1986-01-01 |
| GenBank acession | BC021117 |
| Entrez gene record | 1435 |
| Pubmed identfication | 1540160 |
| RefSeq identity | NM_000757 |
| Havana BLAST/BLAT | OTTHUMG00000011646 |