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Anti-MAP1A/MAP1B LC3 A/B, ALEXA Fluor 594

Anti-MAP1A/MAP1B LC3 A/B, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMAP1A/MAP1B LC3 A/B
SpecificityThis antibody reacts specifically with MAP1A/MAP1B LC3 A/B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
Gene ID81631, 84557
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A disruption to the autophagic process is now associated with the progression of several cancers, LC3, LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), This process of internal cellular turn-over is called autophagy (self-eating), a ubiquitin-like modifier protein, and is facilitated by a pathway of around 16 interacting proteins in the human, called autophagosomes, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, neurodegenerative disorders and cardiac pathologies, respectively, termed LC3-I and LC3-II, where LC3 is widely employed as a marker for autophagy, which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asMAP1A/MAP1B LC3 A/B Antibody
Other nameAnti-MAP1A/MAP1B LC3 A/B
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMAP1A/MAP1B LC3 A/B
Short name Fluor 594, Anti-MAP1A/MAP1B LC3 A/B
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MAP1A/MAP1B LC3 A/B
Identity 6835
Gene MAP1A
Long gene name microtubule associated protein 1A
Synonyms gene MAP1L
Locus 15q15, 3
Discovery year 1992-07-09
GenBank acession U38292
Entrez gene record 4130
Pubmed identfication 7806212 7629894
RefSeq identity NM_002373
Havana BLAST/BLAT OTTHUMG00000059756

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