Name : Anti-MARK2(Ser595) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN7405446433
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MARK2 Ser595 |
| Specificity | This antibody reacts specifically with MARK2(Ser595) |
| Modification | Phosphorylation |
| Modification site | Ser595 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human MARK2 around the phosphorylation site of Ser595 |
| Gene ID | 2011 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Both forms were found to be coexpressed in a number of selected cell lines and tissue samples, EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed, Multiple splice variants exist for this protein, Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2, These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein, microtubule, one containing the exon and the other one lacking it, MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens], stability and cancer |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PAR-1 Par1b PAR-1B |
| Also known as | MARK2(Ser595) Polyclonal Antibody |
| Other name | Anti-MARK2(Ser595) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MARK2(Ser595) |
| Short name | Anti-MARK2(Ser595) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-mitogen-stimulated protein kinase/microtubule affinity-regulating kinase 2(Ser595) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | EMK-1 and EMK1 and PAR-1 and Par-1b and Par1b, MARK2 and IDBG-52754 and ENSG00000072518 and 2011, MARK2 and IDBG-643848 and ENSBTAG00000007825 and 535197, Mark2 and IDBG-138576 and ENSMUSG00000024969 and 13728, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0001764 and neuron migration and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005884 and actin filament and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0008289 and lipid binding and molecular function this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008289: lipid binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008289: lipid binding, this GO :0016772: transferase activity, this GO :0044822: poly(A) RNA binding, this GO :0050321: tau-protein kinase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822: poly(A) RNA binding and also this GO :0050321: tau-protein kinase activity, transferring phosphorus-containing groups and molecular function this GO :0030010 and establishment of cell polarity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045180 and basal cortex and cellular component this GO :0045197 and establishment or maintenance of epithelial cell apical/basal polarity and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050321 and tau-protein kinase activity and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0097427 and microtubule bundle and cellular component, MAP/microtubule affinity-regulating kinase 2 |
| Identity | 3332 |
| Gene | MARK2 |
| Long gene name | microtubule affinity regulating kinase 2 |
| Synonyms gene | EMK1 |
| Synonyms gene name | ELKL motif kinase MAP/microtubule affinity-regulating kinase 2 |
| Synonyms name | ELKL motif kinase 1 serine/threonine kinase protein-serine/threonine kinase Ser/Thr protein kinase PAR-1B |
| Locus | 11q13, 1 |
| Discovery year | 1994-12-08 |
| GenBank acession | BC008771 |
| Entrez gene record | 2011 |
| Pubmed identfication | 9730619 10516437 |
| RefSeq identity | NM_017490 |
| Havana BLAST/BLAT | OTTHUMG00000160504 |