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Anti-MASP (Polyclonal), ALEXA Fluor 594

Anti-MASP (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMASP
SpecificityThis antibody reacts specifically with MASP
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human MASP
Gene ID5648
Swiss ProtP48740
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction, Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5, The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them, Functions in the lectin pathway of complement
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MASP
Also known asMASP Polyclonal Antibody
Other nameAnti-MASP Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMASP
Short nameAnti-MASP (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MASP (polyclonal)
Alternative techniquepolyclonals
Identity 6901
Gene MASP1
Long gene name mannan binding lectin serine peptidase 1
Synonyms gene CRARF PRSS5
Synonyms gene name mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Synonyms name C4/C2 activating component of Ra-reactive factor
Locus 3q27, 3
Discovery year 1995-07-06
GenBank acession D28593
Entrez gene record 5648
Pubmed identfication 8018603 8240317
RefSeq identity NM_001879
Classification Sushi domain containing Proteases, serine
Havana BLAST/BLAT OTTHUMG00000156461
Locus Specific Databases LRG_349

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