Name : Anti-MASP2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2209875378
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MASP2 |
| Specificity | This antibody reacts specifically with MASP2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Secreted |
| Antigen Source | KLH conjugated synthetic peptide derived from human MASP2 |
| Gene ID | 10747 |
| Swiss Prot | O00187 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase, Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | MASP2 Polyclonal Antibody |
| Other name | Anti-MASP2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MASP2 |
| Short name | Anti-MASP2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-mannan-binding lectin serine peptidase 2 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | Extracellular, MAP19 and MASP-2 and MASP1P1 and sMAP, MASP2 and IDBG-633071 and ENSBTAG00000012808 and 505819, MASP2 and IDBG-89176 and ENSG00000009724 and 10747, Masp2 and IDBG-204703 and ENSMUSG00000028979 and 17175, calcium-dependent protein binding, classical pathway and biological process this GO :0008233 and peptidase activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0048306 and calcium-dependent protein binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, lectin pathway and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006508 and proteolysis and biological process this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0001855 and complement component C4b binding and molecular function this GO :0001867 and complement activation, this GO :0001855: complement component C4b binding, this GO :0001855: complement component C4b binding and also this GO :0003824: catalytic activity and also this GO :0004252: serine-type endopeptidase activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008233: peptidase activity and also this GO :0048306: calcium-dependent protein binding, this GO :0003824: catalytic activity, this GO :0004252: serine-type endopeptidase activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008233: peptidase activity, this GO :0048306: calcium-dependent protein binding, mannan-binding lectin serine peptidase 2 |
| Identity | 6902 |
| Gene | MASP2 |
| Long gene name | mannan binding lectin serine peptidase 2 |
| Synonyms gene | MASP1P1 |
| Synonyms gene name | mannan-binding lectin serine protease 2 mannan-binding lectin serine peptidase 1 pseudogene 1 mannan-binding lectin serine protease 1 pseudogene 1 |
| Locus | 1p36, 22 |
| Discovery year | 1998-12-17 |
| GenBank acession | X98400 |
| Entrez gene record | 10747 |
| Pubmed identfication | 9087411 9777418 |
| RefSeq identity | NM_006610 |
| Classification | Sushi domain containing |
| Havana BLAST/BLAT | OTTHUMG00000002121 |
| Locus Specific Databases | MASP2base: Mutation registry for MASP-2 deficiency LRG_82 |