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Anti-MC-1R/MC1 Receptor (Polyclonal), ALEXA Fluor 594

Anti-MC-1R/MC1 Receptor (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMC-1R/MC1 Receptor
SpecificityThis antibody reacts specifically with MC-1R/MC1 Receptor
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human MC-1R
Gene ID4157
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis, Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation, Gene mutations that lead to a loss in function are associated with increased pheomelanin production, Over30 variant alleles have been identified which correlate with skin and hair color, The encoded protein, This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer, Two types of melanin exist: red pheomelanin and black eumelanin, a seven pass transmembrane G protein coupled receptor, controls melanogenesis, providing evidence that this gene is an important component in determining normal human pigment variation, which leads to lighter skin and hair color, This intronless gene encodes the receptor protein for melanocyte -stimulating hormone (MSH)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MC1-R, MC1R, MSH-R, MSHR, MSHR_HUMAN, Melanocortin 1 receptor, Melanocortin 1 receptor alpha melanocyte stimulating hormone receptor, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Melanotropin receptor, SHEP2, CMM5
Also known asMC-1R/MC1 Receptor Polyclonal Antibody
Other nameAnti-MC-1R/MC1 Receptor Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMC-1R/MC1 Receptor
Short nameAnti-MC-1R/MC1 Receptor (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MC-1R/MC1 Receptor (polyclonal)
Alternative techniquepolyclonals

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