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Anti-MCK10 (Tyr513) (Polyclonal), ALEXA Fluor 594

Anti-MCK10 (Tyr513) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Price 516
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMCK10 Tyr513
SpecificityThis antibody reacts specifically with MCK10 (Tyr513)
ModificationPhosphorylation
Modification siteTyr513
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human MCK10 around the phosphorylation site of Tyr513
Gene ID780
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Alternative splicing of this gene results in multiple transcript variants, In addition, In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, Its autophosphorylation is achieved by all collagens so far tested (type I to type VI), The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen, These molecules are involved in the regulation of cell growth, This gene is located on chromosome 6p21, This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain, and brain, and pediatric brain, differentiation and metabolism, esophageal, gastrointestinal tract, lung, ovarian, particularly in the kidney, this protein is significantly over-expressed in several human tumors from breast, 3 in proximity to several HLA class I genes, Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CAK, CD167, CD167a, Cell adhesion kinase, DDR, DDR 1, DDR1, DDR1CD 167, DDR1_HUMAN, Discoidin domain receptor, Discoidin receptor tyrosine kinase isoform a, EDDR 1, Epithelial discoidin domain receptor 1, Epithelial specic receptor kinase, Mammarian carcinoma kinase 10, NTRK 4, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, PTK 3, PTK 3A protein tyrosine kinase 3A, RTK 6, Receptor tyrosine kinase NEP, TRK E, Tyrosine kinase receptor E, p-MCK10 phospho Y513, MCK10 phospho Y513
Also known asMCK10 (Tyr513) Polyclonal Antibody
Other nameAnti-MCK10 (Tyr513) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMCK10 (Tyr513)
Short nameAnti-MCK10 (Tyr513) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MCK10 (Tyr513) (polyclonal)
Alternative techniquepolyclonals

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