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Anti-MCKD2 (Polyclonal), ALEXA Fluor 594

Anti-MCKD2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMCKD2/UMOD
SpecificityThis antibody reacts specifically with MCKD2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Cell membrane, Secreted
Antigen SourceKLH conjugated synthetic peptide derived from mouse MCKD2
Gene ID22242
Swiss ProtQ91X17
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ADMCKD2
Also known asMCKD2 Polyclonal Antibody
Other nameAnti-MCKD2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMCKD2
Short nameAnti-MCKD2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MCKD2 (polyclonal)
Alternative techniquepolyclonals
Identity 6942
Gene MCKD2
Long gene name medullary cystic kidney disease 2 (autosomal dominant)
Locus 16p12
Discovery year 1999-06-02
Pubmed identfication 10330352

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