Name : Anti-Mcl1 (Ser159 + Thr163), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN1953954408
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Mcl1 Ser159 + Thr163 |
| Specificity | Mcl1 (Ser159 + Thr163), These phosphorylation sites are homologous to Ser140 + Thr144 in Mouse and Ser139 + Thr143 in Rat |
| Modification | Phosphorylation |
| Modification site | Ser159 + Thr163 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163 |
| Gene ID | 4170 |
| Swiss Prot | Q07820 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Isoform 1 inhibits apoptosis, Isoform 2 promotes apoptosis, Mediates its effects by interactions with a number of other regulators of apoptosis, and in the maintenance of viability but not of proliferation, Involved in the regulation of apoptosis versus cell survival |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, MCL1, MCL1-ES, MCL1L, MCL1S, Mcl-1, bcl2-L-3, mcl1/EAT, TM |
| Also known as | Mcl1 (Ser159 + Thr163) Antibody |
| Other name | Anti-Mcl1 (Ser159 + Thr163) |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Mcl1 (Ser159 + Thr163) |
| Short name | Anti-Mcl1 (Ser159 + Thr163) Fluor 594 |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-myeloid cell leukemia sequence 1 (BCL2-related) (Ser159 and Thr163) |