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Anti-MeCP2 (Polyclonal), ALEXA Fluor 594

Anti-MeCP2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMeCP2
SpecificityThis antibody reacts specifically with MeCP2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human MeCP2
Gene ID4204
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Each of these proteins, Human proteins MECP2, In contrast to other MBD family members, MBD1, MBD1 and MBD2 can also repress transcription from methylated gene promoters, MBD2, MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD), MECP2, MECP2 gene mutations are the cause of some cases of Rett syndrome, MECP2 is X-linked and subject to X inactivation, MECP2 is dispensible in stem cells, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females, but is essential for embryonic development, is capable of binding specifically to methylated DNA, with the exception of MBD3, DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MECP2
Also known asMeCP2 Polyclonal Antibody
Other nameAnti-MeCP2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMeCP2
Short nameAnti-MeCP2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MeCP2 (polyclonal)
Alternative techniquepolyclonals
Identity 10470
Gene RTT
Long gene name methyl-CpG binding protein 2
Synonyms gene MRX16 MRX79
Synonyms gene name X-linked 16 mental retardation, X-linked 79 Rett syndrome methyl CpG binding protein 2 (Rett syndrome) methyl CpG binding protein 2 , mental retardation
Locus Xq28
Discovery year 1996-09-03
GenBank acession AF158180
Entrez gene record 4204
Pubmed identfication 1606614 10508514
RefSeq identity NM_004992
Classification X-linked mental retardation Methyl-CpG binding domain containing
Havana BLAST/BLAT OTTHUMG00000024229
Locus Specific Databases RettBASE Mental Retardation database LRG_764

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