Name : Anti-MEF2D(Ser444) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN5387849835
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MEF2D Ser444 |
| Specificity | This antibody reacts specifically with MEF2D(Ser444) |
| Modification | Phosphorylation |
| Modification site | Ser444 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser444 |
| Gene ID | 4209 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alternative splicing results in multiple transcript variants, Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, Members of this family are involved in control of muscle and neuronal cell differentiation and development, The encoded protein may also be involved in Parkinson disease and myotonic dystrophy, and are regulated by class II histone deacetylases, suggesting a role in leukemogenesis, MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | MEF2D(Ser444) Polyclonal Antibody |
| Other name | Anti-MEF2D(Ser444) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MEF2D(Ser444) |
| Short name | Anti-MEF2D(Ser444) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-myocyte enhancer factor 2D(Ser444) (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007399 and nervous system development and biological process this GO :0007512 and adult heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function, MEF2D and IDBG-103519 and ENSG00000116604 and 4209, MEF2D and IDBG-631559 and ENSBTAG00000046545 and 100336730, Mef2d and IDBG-159892 and ENSMUSG00000001419 and 17261, nuclei, protein dimerization activity, this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0001958 and endochondral ossification and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977: RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0033613: activating transcription factor binding and also this GO :0042826: histone deacetylase binding and also this GO :0046983: protein dimerization activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0033613: activating transcription factor binding, this GO :0042826: histone deacetylase binding, this GO :0046983: protein dimerization activity, myocyte enhancer factor 2D |
| Identity | 6997 |
| Gene | MEF2D |
| Long gene name | myocyte enhancer factor 2D |
| Locus | 1q22 |
| Discovery year | 1995-02-08 |
| GenBank acession | BC054520 |
| Entrez gene record | 4209 |
| Pubmed identfication | 8269842 |
| RefSeq identity | NM_005920 |
| Classification | Myocyte enhancer factor 2 proteins MADS box family |
| Havana BLAST/BLAT | OTTHUMG00000033095 |