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Anti-MEGF10 (Polyclonal), ALEXA Fluor 594

Anti-MEGF10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMEGF10
SpecificityThis antibody reacts specifically with MEGF10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human MEGF10
Gene ID84466
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is expressed at the cell surface in clusters around cell corpses during engulfment, MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain, MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern, The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1), The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup, which is an ortholog to CED-7, 140 amino acid protein encoded by the human gene MEGF10, MEGF10 is a 1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1780
Also known asMEGF10 Polyclonal Antibody
Other nameAnti-MEGF10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMEGF10
Short nameAnti-MEGF10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-multiple epidermal growth factor-like-domains 10 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target MEGF10 and IDBG-39569 and ENSG00000145794 and 84466, MEGF10 and IDBG-644881 and ENSBTAG00000000329 and 539136, Megf10 and IDBG-148090 and ENSMUSG00000024593 and 70417, Plasma membranes, protein binding, this GO :0001891 and pha this GO cytic cup and cellular component this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0014719 and satellite cell activation and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0014841 and satellite cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0042995 and cell projection and cellular component this GO :0043654 and recognition of apoptotic cell and biological process this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0051147 and regulation of muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, multiple EGF-like-domains 10
Identity 29634
Gene MEGF10
Long gene name multiple EGF like domains 10
Synonyms gene name multiple EGF-like-domains 10
Locus 5q23, 2
Discovery year 2006-03-31
GenBank acession AK021631
Entrez gene record 84466
Pubmed identfication 11347906
RefSeq identity NM_032446
Classification Scavenger receptors
Havana BLAST/BLAT OTTHUMG00000128984

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