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Anti-MEK2(Ser226) (Polyclonal), ALEXA Fluor 594

Anti-MEK2(Ser226) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMEK2 Ser226
SpecificityThis antibody reacts specifically with MEK2(Ser226)
ModificationPhosphorylation
Modification siteSer226
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226
Gene ID5605
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A pseudogene, It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, Jul 2008], Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases, The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax, This kinase is known to play a critical role in mitogen growth factor signal transduction, [provided by RefSeq, a disease characterized by heart defects, and distinctive facial features similar to those found in Noonan syndrome, has been identified for this gene, mental retardation, which is located on chromosome 7, The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MEK2
Also known asMEK2(Ser226) Polyclonal Antibody
Other nameAnti-MEK2(Ser226) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMEK2(Ser226)
Short nameAnti-MEK2(Ser226) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MEK2(Ser226) (polyclonal)
Alternative techniquepolyclonals
Identity 6842
Gene MAP2K2
Long gene name mitogen-activated protein kinase kinase 2
Synonyms gene PRKMK2
Locus 19p13, 3
Discovery year 1993-11-05
GenBank acession L11285
Entrez gene record 5605
Pubmed identfication 8388392
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000134286
Locus Specific Databases LRG_750

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