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Anti-MEK5(Ser311+Thr315) (Polyclonal), ALEXA Fluor 594

Anti-MEK5(Ser311+Thr315) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMEK5 Ser311+Thr315
SpecificityThis antibody reacts specifically with MEK5(Ser311+Thr315)
ModificationPhosphorylation
Modification siteSer311+Thr315
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser311+Thr315
Gene ID5607
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information (MAP kinase kinase family), It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, It is not phosphorylated by RAFA, MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle, RAFB or RAFC and it may interact with GTPases such as CDC42, The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation, This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, This kinase specifically interacts with and activates MAPK7/ERK5, and not with another MAP kinase like P38, as well as by atypical protein kinase C isoforms (aPKCs), MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MEK5 MAPKK5 HsT17454
Also known asMEK5(Ser311+Thr315) Polyclonal Antibody
Other nameAnti-MEK5(Ser311+Thr315) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMEK5(Ser311+Thr315)
Short nameAnti-MEK5(Ser311+Thr315) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MEK5(Ser311+Thr315) (polyclonal)
Alternative techniquepolyclonals
Identity 6845
Gene MAP2K5
Long gene name mitogen-activated protein kinase kinase 5
Synonyms gene PRKMK5
Locus 15q23
Discovery year 1997-11-11
GenBank acession U25265
Entrez gene record 5607
Pubmed identfication 7759517
RefSeq identity NM_145162
Classification Mitogen-activated protein kinase kinases
Havana BLAST/BLAT OTTHUMG00000133264

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