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Anti-Menin (Polyclonal), ALEXA Fluor 594

Anti-Menin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMenin
SpecificityThis antibody reacts specifically with Menin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human Menin
Gene ID4221
Swiss ProtO00255
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binds to the TERT promoter and represses telomerase expression, Functions as a transcriptional regulator, May be involved in DNA repair, May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity), Plays a role in TGFB1-mediated inhibition of cell-proliferation, Positively regulates HOXC8 and HOXC6 gene expression, Represses JUND-mediated transcriptional activation on AP1 sites, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4), as well as that mediated by NFKB subunit RELA, possibly regulating SMAD3 transcriptional activity, Essential component of a MLL/SET1 histone methyltransferase (HMT) complex
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asMenin Polyclonal Antibody
Other nameAnti-Menin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMenin
Short nameAnti-Menin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Menin (polyclonal)
Alternative techniquepolyclonals
Identity 7010
Gene MEN1
Long gene name menin 1
Synonyms gene name multiple endocrine neoplasia I
Synonyms name menin
Locus 11q13
Discovery year 2001-06-22
GenBank acession U93236
Havana BLAST/BLAT OTTHUMG00000045366
Locus Specific Databases UMD Locus Specific Databases LRG_509

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