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Anti-MEPE (Polyclonal), ALEXA Fluor 594

Anti-MEPE (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMEPE
SpecificityThis antibody reacts specifically with MEPE
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MEPE
Gene ID56955
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Expressed in osteocytes and brain, MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment, MEPE is associated with various developmental events such as skeletogenesis, MEPE is secreted in hypophosphatemic osteomalacia tumors, Via its ability to control bone mineralization, bone regeneration and odontogenesis, including OPN (osteopontin) and DSP (dentin sialophosphoprotein), suggesting a possible role in the pathophysiology of bone-related cancers, MEPE is a 525 amino acid extracellular matrix protein
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asMEPE Polyclonal Antibody
Other nameAnti-MEPE Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMEPE
Short nameAnti-MEPE (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MEPE (polyclonal)
Alternative techniquepolyclonals
Identity 13361
Gene MEPE
Long gene name matrix extracellular phosphoglycoprotein
Synonyms gene name extracellular phosphoglycoprotein with ASARM motif (bone) , matrix
Locus 4q22, 1
Discovery year 2000-09-19
GenBank acession AJ276396
Entrez gene record 56955
Pubmed identfication 10945470
Classification SIBLING family
Havana BLAST/BLAT OTTHUMG00000130592

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