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Anti-MHC Class II (Polyclonal), ALEXA Fluor 594

Anti-MHC Class II (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMHC Class II
SpecificityThis antibody reacts specifically with MHC Class II
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsLumenal
Antigen SourceKLH conjugated synthetic peptide derived from human HLA class II histocompatibility antigen DM beta chain
Gene ID3109
Swiss ProtP28068
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO, Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms EF-C
Also known asMHC Class II Polyclonal Antibody
Other nameAnti-MHC Class II Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMHC Class II
Short nameAnti-MHC Class II (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Major histocompabitility complex Class II (polyclonal)
Alternative techniquepolyclonals
Identity 9982
Gene RFX1
Long gene name regulatory factor X1
Synonyms gene name 1 (influences HLA class II expression) , regulatory factor X
Synonyms name trans-acting regulatory factor 1 enhancer factor C MHC class II regulatory factor RFX
Locus 19p13, 1
Discovery year 1991-11-06
Entrez gene record 5989
Pubmed identfication 1505960 8289803
RefSeq identity NM_002918
Classification Regulatory factor X family
Havana BLAST/BLAT OTTHUMG00000181979

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