Name : Anti-MHC Class II (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3729842815
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MHC Class II |
| Specificity | This antibody reacts specifically with MHC Class II |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Lumenal |
| Antigen Source | KLH conjugated synthetic peptide derived from human HLA class II histocompatibility antigen DM beta chain |
| Gene ID | 3109 |
| Swiss Prot | P28068 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO, Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | EF-C |
| Also known as | MHC Class II Polyclonal Antibody |
| Other name | Anti-MHC Class II Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MHC Class II |
| Short name | Anti-MHC Class II (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Major histocompabitility complex Class II (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 9982 |
| Gene | RFX1 |
| Long gene name | regulatory factor X1 |
| Synonyms gene name | 1 (influences HLA class II expression) , regulatory factor X |
| Synonyms name | trans-acting regulatory factor 1 enhancer factor C MHC class II regulatory factor RFX |
| Locus | 19p13, 1 |
| Discovery year | 1991-11-06 |
| Entrez gene record | 5989 |
| Pubmed identfication | 1505960 8289803 |
| RefSeq identity | NM_002918 |
| Classification | Regulatory factor X family |
| Havana BLAST/BLAT | OTTHUMG00000181979 |