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Anti-MICA+MICB (Polyclonal), ALEXA Fluor 594

Anti-MICA+MICB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMICA+MICB
SpecificityThis antibody reacts specifically with MICA+MICB
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human MICB
Gene ID 4277, 100507436
Swiss Prot Q29980, Q29983
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding to KLRK1 leads to cell lysis, Ligand for the KLRK1/NKG2D receptor, Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PERB11, 1
Also known asMICA+MICB Polyclonal Antibody
Other nameAnti-MICA+MICB Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMICA+MICB
Short nameAnti-MICA+MICB (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Major histocompabitility complex class I polypeptide-related sequence A+Major histocompabitility complex class I polypeptide-related sequence B (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target Cell surfaces, MHC class I polypeptide-related sequence B, MICA and IDBG-77578 and ENSG00000204520 and 100507436, MICB and IDBG-77697 and ENSG00000204516 and 4277, PERB11, Plasma membranes, natural killer cell lectin-like receptor binding, protein binding, this GO :0002429 and immune response-activating cell surface receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019835 and cytolysis and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0046629 and gamma-delta T cell activation and biological process this GO :0046703 and natural killer cell lectin-like receptor binding and molecular function this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050776 and regulation of immune response and biological process, this GO :0005515 and protein binding and molecular function this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019882 and antigen processing and presentation and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0046703: natural killer cell lectin-like receptor binding, this GO :0046703: natural killer cell lectin-like receptor binding, 2, MHC class I polypeptide-related sequence A
Identity 7090
Gene MICA
Long gene name MHC class I polypeptide-related sequence A
Locus 6p21, 33
Discovery year 1994-05-16
GenBank acession L14848
Entrez gene record 100507436
Pubmed identfication 8022771
RefSeq identity NM_001177519
Classification C1-set domain containing
Havana BLAST/BLAT OTTHUMG00000031073
Locus Specific Databases IMGT/HLA Database

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