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Anti-MMS19 (Polyclonal), ALEXA Fluor 594

Anti-MMS19 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMMS19
SpecificityThis antibody reacts specifically with MMS19
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MMS 19
Gene ID64210
Swiss ProtQ96T76
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information As part of the mitotic spindle-associated MMXD complex, FANCJ and RTEL1, In the CIA complex, Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription, via its role in iron-sulfur insertion into some component of the TFIIH-machinery, Key component of the cytosolic iron-sulfur protein assembly (CIA) complex
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MET18 hMMS19
Also known asMMS19 Polyclonal Antibody
Other nameAnti-MMS19 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMMS19
Short nameAnti-MMS19 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MMS19 (polyclonal)
Alternative techniquepolyclonals
Identity 13824
Gene MMS19
Long gene name MMS19 homolog, cytosolic iron-sulfur assembly component
Synonyms gene MMS19L
Synonyms gene name MMS19 nucleotide excision repair homolog (S, cerevisiae)
Synonyms name MET18 homolog (S, cerevisiae)
Locus 10q24, 1
Discovery year 2000-12-21
GenBank acession AF007151
Entrez gene record 64210
Pubmed identfication 11071939 22678362 22678361
Classification Nucleotide excision repair Cytosolic iron-sulfur assembly components
Havana BLAST/BLAT OTTHUMG00000018857

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