Name : Anti-MNAT1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2827717237
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MNAT1 |
| Specificity | This antibody reacts specifically with MNAT1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus |
| Antigen Source | KLH conjugated synthetic peptide derived from human MNAT1 |
| Gene ID | 4331 |
| Swiss Prot | P51948 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | CAK activates the cyclin-associated kinases CDK1, CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), CDK2, CDK4 and CDK6 by threonine phosphorylation, Involved in cell cycle control and in RNA transcription by RNA polymerase II, allowing its escape from the promoter and elongation of the transcripts, Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MAT1 RNF66 |
| Also known as | MNAT1 Polyclonal Antibody |
| Other name | Anti-MNAT1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MNAT1 |
| Short name | Anti-MNAT1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, cyclin H assembly factor (Xenopus laevis) (polyclonal), antibody to-menage a trois homolog 1 |
| Alternative technique | polyclonals |
| Alternative to gene target | CAP35 and MAT1 and RNF66 and TFB3, DNA damage removal and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005675 and holo TFIIH complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006360 and transcription from RNA polymerase I promoter and biological process this GO :0006361 and transcription initiation from RNA polymerase I promoter and biological process this GO :0006362 and transcription elongation from RNA polymerase I promoter and biological process this GO :0006363 and termination of RNA polymerase I transcription and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006368 and transcription elongation from RNA polymerase II promoter and biological process this GO :0006370 and 7-methylguanosine mRNA capping and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007049 and cell cycle and biological process this GO :0007512 and adult heart development and biological process this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008353 and RNA polymerase II carboxy-terminal domain kinase activity and molecular function this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0021591 and ventricular system development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0050434 and positive regulation of viral transcription and biological process this GO :0051592 and response to calcium ion and biological process, MNAT1 and IDBG-646752 and ENSBTAG00000030801 and 534176, MNAT1 and IDBG-8368 and ENSG00000020426 and 4331, Mnat1 and IDBG-148230 and ENSMUSG00000021103 and 17420, cyclin H assembly factor (Xenopus laevis), nuclei, protein N-terminus binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000718 and nucleotide-excision repair, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008094: DNA-dependent ATPase activity and also this GO :0008270: zinc ion binding and also this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity and also this GO :0047485: protein N-terminus binding, this GO :0008094: DNA-dependent ATPase activity, this GO :0008270: zinc ion binding, this GO :0008353: RNA polymerase II carboxy-terminal domain kinase activity, this GO :0047485: protein N-terminus binding, menage a trois homolog 1 |
| Identity | 7181 |
| Gene | MNAT1 |
| Long gene name | CDK activating kinase assembly factor , MNAT1 |
| Synonyms gene name | cyclin H assembly factor (Xenopus laevis) MNAT CDK-activating kinase assembly factor 1 , menage a trois 1 (CAK assembly factor) menage a trois homolog 1 |
| Synonyms name | CDK-activating kinase assembly factor |
| Locus | 14q23, 1 |
| Discovery year | 1997-10-09 |
| GenBank acession | X87843 |
| Entrez gene record | 4331 |
| Pubmed identfication | 9465303 |
| RefSeq identity | NM_002431 |
| Classification | Nucleotide excision repair Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000152340 |