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Anti-MO25 alpha/CAB39 (Polyclonal), ALEXA Fluor 594

Anti-MO25 alpha/CAB39 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMO25 alpha/CAB39
SpecificityThis antibody reacts specifically with MO25 alpha/CAB39
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MO25 alpha/CAB39
Gene ID51719
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, CAB39) is a 40-kDa protein that, LKB1-STRAD-MO25 activity is not increased by muscle contraction, Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK), The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle, The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS), This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase, however, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, Mouse protein 25 alpha (MO25 alpha
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CGI-66 MO25
Also known asMO25 alpha/CAB39 Polyclonal Antibody
Other nameAnti-MO25 alpha/CAB39 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMO25 alpha/CAB39
Short nameAnti-MO25 alpha/CAB39 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MO25 a/CAB39 (polyclonal)
Alternative techniquepolyclonals
Identity 20292
Gene CAB39
Long gene name calcium binding protein 39
Locus 2q37, 1
Discovery year 2004-07-02
GenBank acession AF113536
Entrez gene record 51719
RefSeq identity NM_016289
Havana BLAST/BLAT OTTHUMG00000133220

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