Filters

Anti-MOUSE MDM2 Antibody

Anti-MOUSE MDM2 Antibody size: 50ug 475

Supplier MBS POLYCLONALS 1
Price 475
Size 50ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI MOUSE MDM2
Alternative name2RABBIT ANTI Murine MDM2
Alternative name3Lapin ANTI Mus musculus MDM2
Alternative name4MDM2
Alternative name5N/A
Other names Double minute 2 protein, E3 ubiquitin-protein ligase Mdm2, E3 ubiquitin-protein ligase Mdm2, Oncoprotein Mdm2, double minute 2 protein, oncoprotein Mdm2, p53-binding protein Mdm2, p53-binding protein Mdm2, transformed mouse 3T3 cell double minute 2, E3 ubiquitin-protein ligase Mdm2
Gene nameMDM2
Gene name synonimsN/A
Other gene names 1700007J15Rik, AA415488, Mdm-2, Mdm2, N/A, Mdm2
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityMouse
Specificity and cross-reactivity Mdm2 also interacts with the retinoblastoma (RB) protein and E2F-1, _x000D__x000D_Mdm2 activity is controlled by self-ubiquitination, a nuclear phosphoprotein that controls intracellular levels of the tumour suppressor protein p53 by ubiquitination and subsequent proteasomal degradation, however activation of the PI3K/PKB pathway leads to phosphorylation of Mdm2 at Ser185, to promote G1-S phase transition in the cell cycle, which stabilises the protein, MDM2 This item detects murine Mdm2
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
ConcentrationIgG concentration 500ug/1000ul
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: Western Blot (WB), ELISA (EIA)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetMDM2
Short nameAnti-MOUSE MDM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-MOUSE MDM2 (Antibody to)
Alternative techniqueantibodies
Identity 6973
Gene MDM2
Long gene name MDM2 proto-oncogene
Synonyms gene name E3 ubiquitin protein ligase , human homolog of, mouse double minute 2, p53 binding protein (mouse) Mdm2 p53 binding protein homolog (mouse) MDM2 proto-oncogene, p53-binding protein Mdm2, transformed 3T3 cell double minute 2
Synonyms HDM2 MGC5370
Locus 12q15
Discovery year 1993-12-10
Entrez gene record 4193
Pubmed identfication 1614537 16905769
RefSeq identity NM_006880
Classification Zinc fingers RANBP2-type
Havana BLAST/BLAT OTTHUMG00000142827

Similar products

Subscribe to our Newsletter