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Anti-MPP5/PALS1 (Polyclonal), ALEXA Fluor 594

Anti-MPP5/PALS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMPP5/PALS1
SpecificityThis antibody reacts specifically with MPP5/PALS1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MPP5/PALS1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Because tumors exhibit perturbations in epithelial polarity, Loss of Pals1 function results in delayed polarization, Pals1, Pals1 presents a new potential target in the study of carcinogenesis, Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes, decreased transepithelial electrical resistance and an inability to form lumenal cysts, importantly, mediates interaction between the two complexes via interaction with Par6, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex, Two highly conserved complexes are responsible for the assembly of tight junctions
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PALS1 FLJ12615
Also known asMPP5/PALS1 Polyclonal Antibody
Other nameAnti-MPP5/PALS1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMPP5/PALS1
Short nameAnti-MPP5/PALS1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MPP5/PALS1 (polyclonal)
Alternative techniquepolyclonals
Identity 18669
Gene MPP5
Long gene name membrane palmitoylated protein 5
Synonyms gene name membrane protein, palmitoylated 5 , palmitoylated 5 (MAGUK p55 subfamily member 5) membrane protein
Synonyms name stardust protein associated with Lin-7 1
Locus 14q23, 3
Discovery year 2002-05-23
GenBank acession AK022677
Entrez gene record 64398
Pubmed identfication 11927608
RefSeq identity NM_022474
Classification Crumbs complex Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000171243

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