Name : Anti-MPZL2/EVA1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8850648143
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MPZL2/EVA1 |
| Specificity | This antibody reacts specifically with MPZL2/EVA1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human MPZL2/EVA1 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression, It is highly homologous to the myelin protein zero and, Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis, Jul 2008], The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, This gene is expressed in the thymus and in several epithelial structures early in embryogenesis, Two transcript variants encoding the same protein have been found for this gene, [provided by RefSeq, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton, Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | EVA |
| Also known as | MPZL2/EVA1 Polyclonal Antibody |
| Other name | Anti-MPZL2/EVA1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MPZL2/EVA1 |
| Short name | Anti-MPZL2/EVA1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-myelin protein zero-like 2/EVA1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | EVA and EVA1, MPZL2 and IDBG-631254 and ENSBTAG00000033510 and 540423, MPZL2 and IDBG-73587 and ENSG00000149573 and 10205, Mpzl2 and IDBG-159117 and ENSMUSG00000032092 and 14012, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0033077 and T cell differentiation in thymus and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, myelin protein zero-like 2 |
| Identity | 3496 |
| Gene | MPZL2 |
| Long gene name | myelin protein zero like 2 |
| Synonyms gene | EVA1 |
| Synonyms gene name | epithelial V-like antigen 1 |
| Locus | 11q24 |
| Discovery year | 1999-11-22 |
| GenBank acession | AF275945 |
| Entrez gene record | 10205 |
| Pubmed identfication | 9585423 |
| RefSeq identity | NM_005797 |
| Classification | V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166967 |