Anti-MRC2 (Polyclonal), ALEXA Fluor 594

Anti-MRC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	MRC2
Specificity	This antibody reacts specifically with MRC2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human MRC2/CD280
Gene ID	9902
Swiss Prot	Q9UBG0
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis, May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, May contribute to cellular uptake, May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs), May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover, and thus may regulate protease activity at the cell surface, remodeling and degradation of extracellular collagen matrices, May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	KIAA0709 ENDO180 CLEC13E CD280
Also known as	MRC2 Polyclonal Antibody
Other name	Anti-MRC2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	MRC2
Short name	Anti-MRC2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, C type 2 (polyclonal), antibody to-mannose receptor
Alternative technique	polyclonals
Alternative to gene target	C type 2, CD280 and CLEC13E and ENDO180 and UPARAP, MRC2 and IDBG-63031 and ENSG00000011028 and 9902, MRC2 and IDBG-641433 and ENSBTAG00000015739 and 529049, Mrc2 and IDBG-213230 and ENSMUSG00000020695 and 17534, Plasma membranes, carbohydrate binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0006897 and endocytosis and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0030574 and collagen catabolic process and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0030246: carbohydrate binding, this GO :0005518: collagen binding, this GO :0030246: carbohydrate binding, mannose receptor
Identity	16875
Gene	MRC2
Long gene name	mannose receptor C type 2
Synonyms gene name	C type 2 , mannose receptor
Synonyms name	C-type lectin domain family 13 member E endocytic receptor 180
Locus	17q23
Discovery year	2002-09-24
GenBank acession	AB014609
Entrez gene record	9902
Pubmed identfication	9734811 8702911
Classification	CD molecules C-type lectin domain family
Havana BLAST/BLAT	OTTHUMG00000179178

Anti-MRC2 (Polyclonal), ALEXA Fluor 594

Anti-MRC2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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