Anti-MTA2 (Polyclonal), ALEXA Fluor 594

Anti-MTA2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	MTA2
Specificity	This antibody reacts specifically with MTA2
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human MTA2
Gene ID	9219
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	A similar protein, Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, MTA1 contains a single SH3-binding motif and a zinc finger domain, MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin, MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis, MTA2, Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, Structurally, along with a region similar to the co-repressor protein N-Cor, also designated MTA1-L1 (MTA1-like protein 1), and therefore may be an indicator for assessing the potential malignancies of various tumors, gastrointestinal and breast carcinomas, increase mammary cell motility and potentiate growth, shares more than 55% sequence homology with MTA1 and is ubiquitously expressed, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity, MTA1 is a component of the NURD (nucleosome remodeling and histone deacetylation) complex
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	MTA1-L1
Also known as	MTA2 Polyclonal Antibody
Other name	Anti-MTA2 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	MTA2
Short name	Anti-MTA2 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-MTA2 (polyclonal)
Alternative technique	polyclonals
Identity	7411
Gene	MTA2
Long gene name	metastasis associated 1 family member 2
Synonyms gene	MTA1L1
Synonyms gene name	member 2 , metastasis associated gene family
Locus	11q12, 3
Discovery year	1999-05-17
GenBank acession	AB016591
Entrez gene record	9219
Pubmed identfication	9929979
RefSeq identity	NM_004739
Classification	GATA zinc finger domain containing NuRD complex Myb/SANT domain containing
Havana BLAST/BLAT	OTTHUMG00000167684

Anti-MTA2 (Polyclonal), ALEXA Fluor 594

Anti-MTA2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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