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Anti-MTMR2 (Polyclonal), ALEXA Fluor 594

Anti-MTMR2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMTMR2
SpecificityThis antibody reacts specifically with MTMR2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MTMR2
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3, MTMR2 interacts with MTMR5, MTMR3 and MTMR4 can either interact with each other or self associate, MTMR6 regulates the activity of the calcium-activated potassium channel 3, MTMR9 regulates the activity of MTMR7 and MTMR8, Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), They are protein tyrosine phosphatases that utilize inositol phospholipids, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization, as substrates, focally folded myelin sheaths and demyelination, rather than phosphoproteins, which is characterized by reduced nerve conduction velocities, 1, 5)P2, Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1073
Also known asMTMR2 Polyclonal Antibody
Other nameAnti-MTMR2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMTMR2
Short nameAnti-MTMR2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-MTMR2 (polyclonal)
Alternative techniquepolyclonals
Identity 7450
Gene MTMR2
Long gene name myotubularin related protein 2
Synonyms gene CMT4B
Synonyms name phosphatidylinositol-3-phosphatase phosphoinositide-3-phosphatase
Locus 11q21
Discovery year 1999-02-05
GenBank acession U58033
Entrez gene record 8898
Pubmed identfication 8640223 9736772
RefSeq identity NM_016156
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000153837
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_257

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