Name : Anti-MUL1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2448396279
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | MUL1 |
| Specificity | This antibody reacts specifically with MUL1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human MUL1/RNF218 |
| Gene ID | 79594 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin, Inhibits cell growth, Promotes mitochondrial fragmentation and influences mitochondrial localization, When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis, E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ12875 MULAN RNF218 MAPL GIDE |
| Also known as | MUL1 Polyclonal Antibody |
| Other name | Anti-MUL1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | MUL1 |
| Short name | Anti-MUL1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-mitochondrial E3 ubiquitin protein ligase 1 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | MUL1 and IDBG-645664 and ENSBTAG00000020850 and 508406, MUL1 and IDBG-92888 and ENSG00000090432 and 79594, Mul1 and IDBG-199848 and ENSMUSG00000041241 and 68350, identical protein binding, nuclei, this GO :0000266 and mitochondrial fission and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010637 and negative regulation of mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016925 and protein sumoylation and biological process this GO :0019789 and SUMO ligase activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0031307 and integral component of mitochondrial outer membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0033235 and positive regulation of protein sumoylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050821 and protein stabilization and biological process this GO :0051646 and mitochondrion localization and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060339 and negative regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071650 and negative regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0090141 and positive regulation of mitochondrial fission and biological process this GO :1901028 and regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019789: SUMO ligase activity and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042802: identical protein binding, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019789: SUMO ligase activity, this GO :0031625: ubiquitin protein ligase binding, this GO :0042802: identical protein binding, mitochondrial E3 ubiquitin protein ligase 1 |
| Identity | 25762 |
| Gene | MUL1 |
| Long gene name | mitochondrial E3 ubiquitin protein ligase 1 |
| Synonyms gene | C1orf166 |
| Synonyms gene name | chromosome 1 open reading frame 166 |
| Synonyms name | ring finger protein 218 mitochondria-anchored protein ligase growth inhibition and death E3 ligase mitochondrial ubiquitin ligase activator of NFKB 1 |
| Locus | 1p36, 12 |
| Discovery year | 2005-07-19 |
| GenBank acession | BC014010 |
| Entrez gene record | 79594 |
| Pubmed identfication | 18591963 12761501 18213395 18207745 |
| RefSeq identity | NM_024544 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000002838 |