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Anti-MYBPC3 (Polyclonal), ALEXA Fluor 594

Anti-MYBPC3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMYBPC3
SpecificityThis antibody reacts specifically with MYBPC3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MYBPC3
Gene ID4607
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle, MHC and native thin filaments, MYBPC3 binds F-Actin, Mutations in the MYBPC3 gene lead mainly to truncation of the protein, Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction, The MYBPC3 gene maps to chromosome 11p11, a heart disorder characterized by ventricular hypertrophy, and modifies the activity of Actin-activated myosin ATPase, which often involves the interventricular septum and is usually asymmetric, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), 2, MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MYBP-C FHC
Also known asMYBPC3 Polyclonal Antibody
Other nameAnti-MYBPC3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMYBPC3
Short nameAnti-MYBPC3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, cardiac (polyclonal), antibody to-myosin binding protein C
Alternative techniquepolyclonals
Alternative to gene target CMD1MM and CMH4 and FHC and LVNC10 and MYBP-C, Cytoplasm, MYBPC3 and IDBG-43206 and ENSG00000134571 and 4607, MYBPC3 and IDBG-637371 and ENSBTAG00000021707 and 767614, Mybpc3 and IDBG-190220 and ENSMUSG00000002100 and 17868, cardiac, metal ion binding, this GO :0001671 and ATPase activator activity and molecular function this GO :0002027 and regulation of heart rate and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005863 and striated muscle myosin thick filament and cellular component this GO :0006936 and muscle contraction and biological process this GO :0006942 and regulation of striated muscle contraction and biological process this GO :0007155 and cell adhesion and biological process this GO :0008016 and regulation of heart contraction and biological process this GO :0008307 and structural constituent of muscle and molecular function this GO :0014705 and C zone and cellular component this GO :0017022 and myosin binding and molecular function this GO :0030016 and myofibril and cellular component this GO :0030017 and sarcomere and cellular component this GO :0030049 and muscle filament sliding and biological process this GO :0031034 and myosin filament assembly and biological process this GO :0031432 and titin binding and molecular function this GO :0031672 and A band and cellular component this GO :0032036 and myosin heavy chain binding and molecular function this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0032971 and regulation of muscle filament sliding and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045214 and sarcomere organization and biological process this GO :0046872 and metal ion binding and molecular function this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0060048 and cardiac muscle contraction and biological process, this GO :0001671: ATPase activator activity, this GO :0001671: ATPase activator activity and also this GO :0003779: actin binding and also this GO :0005515: protein binding and also this GO :0008307: structural constituent of muscle and also this GO :0017022: myosin binding and also this GO :0031432: titin binding and also this GO :0032036: myosin heavy chain binding and also this GO :0042802: identical protein binding and also this GO :0046872: metal ion binding, this GO :0003779: actin binding, this GO :0005515: protein binding, this GO :0008307: structural constituent of muscle, this GO :0017022: myosin binding, this GO :0031432: titin binding, this GO :0032036: myosin heavy chain binding, this GO :0042802: identical protein binding, this GO :0046872: metal ion binding, myosin binding protein C
Identity 7551
Gene MYBPC3
Long gene name cardiac , myosin binding protein C
Synonyms gene CMH4
Synonyms gene name cardiac , myosin-binding protein C
Locus 11p11, 2
Discovery year 1995-05-30
GenBank acession X84075
Entrez gene record 4607
Pubmed identfication 7744002 8358441
Classification I-set domain containing Myosin binding proteins Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000166986
Locus Specific Databases FHC Mutation Database LRG_386

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