Name : anti-MyD88 Antibody [2E9C2]
Supplier : PROSCIENCE
Price :180
SKU : GEN7022589716
| Gene info | MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation, MyD88 gene is expressed in many tissues, MyD88 has been identified as an adapter molecule in the IL-1 signaling pathway, MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin, MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors, which are members in the Toll/IL-1R family of receptors, MyD88 Monoclonal Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP |
| Gene names | MyD88 Antibody [2E9C2] : MYD88D |
| Antibodie's label | unlabelled serum |
| Purity | MyD88 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in | Mouse |
| Type | Monoclonal |
| Monoclonal | 2E9C2 |
| Immunoglobulin | IgG2b |
| Antigen | Mouse monoclonal MyD88 antibody was made against a recombinant protein corresponding to amino acids 176 to 280 of human MyD88 |
| Immuno application | Western Blot, immuno fluorescence, immuno-histo-chemistry, ELISA |
| Antibody advice | Antibody can also be used for immunohistochemistry starting at 2, For immunofluorescence start at 20 ug/mL, 5 ug/mL, MyD88 antibody can be used for detection of MyD88 by Western blot at 2 ug/mL |
| Suspention, pH, azide | 02% sodium azide, MyD88 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at | stable for one year, MyD88 monoclonal antibody can be stored at -20 grades C |
| Works with | Mouse, Human |
| Omim nr | 1814020 |
| Ncbi nr | AAC50954 |
| Vial with antibody | in solution |
| Quantity per ml | 1 mg/mL |
| NCBI GENE nr | 4615 |
| GENE symbol | MYD88 |
| Antigene name | myeloid differentiation primary response gene (88) |
| Source | Homo sapiens |
| Protein nr | Q99836 |
| Description | Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target | MyD88 [2E9C2] |
| Short name | anti-MyD88 Antibody [2E9C2] |
| Technique | antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name | antibody to-myeloid differentiation primary response 88 (Antibody to) [2E9C2] |
| Alternative technique | antibodies |