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Anti-MYLK2 (Polyclonal), ALEXA Fluor 594

Anti-MYLK2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideMYLK2
SpecificityThis antibody reacts specifically with MYLK2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human MYLK2
Gene ID85366
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CaMKII, CaMKIV and myosin light chain kinases (MYLK, MYLK appears to be a target for PAKs (p21-activated kinases), MYLK2 (also designated skMLCK), Multiple transcript variants are described for the MYLK gene, Non-muscle, PAK1 interaction with MYLK results in a decrease in MYLK activity and myosin light chain phosphorylation, Smooth-muscle and non-muscle MYLK isoforms are expressed in a wide variety of adult and fetal tissues, The MYLK gene (also designated MYLK1) encodes both smooth muscle and non-muscle isoforms as well as telokin, The MYLK kinases phosphorylate myosin regulatory light chains to catalyze myosin interaction with actin filaments resulting in contractile activity, The skeletal/cardiac muscle isoforms of MYLK are encoded by a separate gene, a small C-terminal isoform expressed only in smooth muscle with the capacity to stabilize unphosphorylated myosin filaments, also designated MLCK), smooth muscle and skeletal/cardiac muscle MYLK isoforms exist, The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms skMLCK KMLC MLCK2
Also known asMYLK2 Polyclonal Antibody
Other nameAnti-MYLK2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetMYLK2
Short nameAnti-MYLK2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-myosin light epitope kinase 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target MYLK2 and IDBG-64011 and ENSG00000101306 and 85366, MYLK2 and IDBG-641556 and ENSBTAG00000014930 and 533378, Mylk2 and IDBG-209914 and ENSMUSG00000027470 and 228785, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004683 and calmodulin-dependent protein kinase activity and molecular function this GO :0004687 and myosin light chain kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006941 and striated muscle contraction and biological process this GO :0007274 and neuromuscular synaptic transmission and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0014816 and satellite cell differentiation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004683: calmodulin-dependent protein kinase activity and also this GO :0004687: myosin light chain kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005516: calmodulin binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004683: calmodulin-dependent protein kinase activity, this GO :0004687: myosin light chain kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005516: calmodulin binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0030017 and sarcomere and cellular component this GO :0032971 and regulation of muscle filament sliding and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0055008 and cardiac muscle tissue morphogenesis and biological process this GO :0060048 and cardiac muscle contraction and biological process, myosin light chain kinase 2
Identity 16243
Gene MYLK2
Long gene name myosin light chain kinase 2
Synonyms gene name myosin light chain kinase 2, skeletal muscle
Synonyms name skeletal muscle myosin light chain kinase
Locus 20q11, 21
Discovery year 2001-07-31
GenBank acession AF325549
Entrez gene record 85366
RefSeq identity NM_033118
Havana BLAST/BLAT OTTHUMG00000032194
Locus Specific Databases LRG_392

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