Name : Anti-N-cadherin (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7800601447
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | N-cadherin |
| Specificity | This antibody reacts specifically with N-cadherin |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human N-cadherin |
| Gene ID | 1000 |
| Swiss Prot | P19022 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2 may be involved in neuronal recognition mechanism, CDH2-mediated anchorage is affected, In hippocampal neurons, They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types, leading to modulate neural stem cell quiescence, may regulate dendritic spine density (By similarity), Cadherins are calcium-dependent cell adhesion proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CDHN CD325 |
| Also known as | N-cadherin Polyclonal Antibody |
| Other name | Anti-N-cadherin Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | N-cadherin |
| Short name | Anti-N-cadherin (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-N-cadherin (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 1759 |
| Gene | CDH2 |
| Long gene name | cadherin 2 |
| Synonyms gene | NCAD |
| Synonyms gene name | N-cadherin (neuronal) , cadherin 2, type 1 |
| Synonyms name | N-cadherin |
| Locus | 18q12, 1 |
| Discovery year | 1991-09-13 |
| GenBank acession | S42303 |
| Entrez gene record | 1000 |
| Pubmed identfication | 2384753 7731968 2216790 |
| RefSeq identity | NM_001792 |
| Classification | Type I classical cadherins CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000059940 |