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Anti-N-cadherin (Polyclonal), ALEXA Fluor 594

Anti-N-cadherin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideN-cadherin
SpecificityThis antibody reacts specifically with N-cadherin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human N-cadherin
Gene ID1000
Swiss ProtP19022
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2 may be involved in neuronal recognition mechanism, CDH2-mediated anchorage is affected, In hippocampal neurons, They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types, leading to modulate neural stem cell quiescence, may regulate dendritic spine density (By similarity), Cadherins are calcium-dependent cell adhesion proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CDHN CD325
Also known asN-cadherin Polyclonal Antibody
Other nameAnti-N-cadherin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetN-cadherin
Short nameAnti-N-cadherin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-N-cadherin (polyclonal)
Alternative techniquepolyclonals
Identity 1759
Gene CDH2
Long gene name cadherin 2
Synonyms gene NCAD
Synonyms gene name N-cadherin (neuronal) , cadherin 2, type 1
Synonyms name N-cadherin
Locus 18q12, 1
Discovery year 1991-09-13
GenBank acession S42303
Entrez gene record 1000
Pubmed identfication 2384753 7731968 2216790
RefSeq identity NM_001792
Classification Type I classical cadherins CD molecules
Havana BLAST/BLAT OTTHUMG00000059940

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